Emerging Models

The Taconic Emerging Models program offers access to developing models sponsored by various Principal Investigators. Animal Models enrolled in the Taconic Emerging Models program are listed below in order by sponsor, gene of interest, and model number. To place an order, please click on the order button above. Some Emerging Models require execution of Material Transfer Agreements (MTAs) before orders may be placed. Please check the individual model pages for that information. For information on how to place an order or regarding MTAs, please contact Taconic Customer Service.

NIAID Exchange Models	Taconic Emerging Models
Taconic tADMET™ Models	Central Institute for Experimental Animals and In-Vivo Science International Sponsored Emerging Model
Ludwig Institute Sponsored Emerging Model	The ALS Association Sponsored Emerging Model
Light Producing Transgenic Animal Models	The Michael J. Fox Foundation Parkinson's Disease Models
Discontinued Emerging Models

NIAID Exchange Models Available From Taconic

Model Name	Nomenclature	Taconic Model Number	Field of Application	Sponsoring Institution & Investigator
B10.Q/Ai	B10.D1-H2q/SgAi	4059	Immunology	NIAID Schwartz
CCR1 Knockout	B6.129S4-Ccr1tm1Gao N10+N5	4087	Immunology	NIAID Schwartz
Rag2 Knockout/Transgenic DO11.10 T Cell Receptor	B10.D2-Rag2tm1Fwa Tg(DO11.10)10Dlo/AiTac	4091	Immunology	NIAID Schwartz
Rag2 Knockout/Transgenic Cyt5CC7 T Cell Receptor	B10.A-Rag2tm1Fwa H2-T18a Tg (Tcra5CC7,Tcrb5CC7)lwep	4094	Immunology	NIAID Schwartz
Rag2/II2rg Double Knockout	B10;B6-Rag2tm1Fwa II2rgtm1Wjl	4111	Immunology	NIAID Schwartz
Tcrα Knockout/Transgenic LCMV P14 T Cell Receptor	B6.Cg-Tcrαtm1Mom Tg(TcrLCMV)327Sdz	4138	Immunology	NIAID Schwartz
Abb Knockout/Transgenic HLA-DR4	B6.129S2-H2-Ab1tm1Gru Tg(HLA-DRA/H2-Ea,HLA-DRB1*0401/H2-Eb)1Kito	4149	Immunology	NIAID Schwartz
CX3CR1 Knockout	B6.129-Cx3cr1tm1Zm	4167	Immunology	NIAID Schwartz
Fpr1 Knockout	C57BL/6NTac-Fpr1tm1Gao N6	4169	Immunology	NIAID
Rag1 Knockout/Transgenic OT-I T Cell Receptor	B6.129S7-Rag1tm1Mom Tg(TcraTcrb)1100Mjb N9+N1	4175	Immunology	NIAID Schwartz
II4ra Knockout	BALB/cJ-Il4ratm1Sz	4177	Immunology	NIAID Schwartz
Cd4-cre Transgenic	B6.Cg-Tg(CD4-cre)1Cwi N9	4196	Immunology	NIAID Schwartz
Lck-cre Transgenic	B6.Cg-Tg(Lck-cre)1Cwi N9	4197	Immunology	NIAID Schwartz
Flt3l Knockout	C57BL/6-flt3Ltm1Imx	4207	Immunology	NIAID Schwartz
H2-Kb H2-Db Double Knockout	B6.129P2-H2-Kbtm1 H2-Dbtm1 N12	4215	Immunology	NIAID Schwartz
H2-Kb Knockout	B6.129P2-H2-Kbtm1 N12	4216	Immunology	NIAID Schwartz
H2-Db	B6.129P2-H2-Dbtm1 N12	4217	Immunology	NIAID Schwartz
Rag2 Knockout/Transgenic DO11.10 T Cell Receptor	C.Cg-Rag2tm1Fwa Tg(DO11.10)10Dlo	4219	Immunology	NIAID Schwartz
Rag1 Knockout/Transgenic OT-II T Cell Receptor	B6.129S7-Rag1tm1Mom Tg(TcraTcrb)425Cbn	4234	Immunology	NIAID Schwartz
Nos2 Knockout	B6.129S2-Nos2tm1MrI N12	4236	Immunology	NIAID Schwartz
LTH-1 Transgenic	B6.SJL-Tg(Lck-tTA)1Dim N10	4245	Immunology	NIAID Schwartz
IL15 Knockout	C57BL/6NTac-IL15tm1Imx N5	4269	Immunology	NIAID Schwartz
Transgenic D011.10 T Cell Receptor/Transgenic CAR	BALB/cJ-Tg(DO11.10)10Dlo Tg(CARΔ-1)1Jdgr	4285	Immunology	NIAID Schwartz
Rag2 Knockout/Transgenic LCMV-P14 T Cell Receptor	B10.Cg-Rag2tm1Fwa Tg(TcrLCMV)327Sdz	4356	Immunology	NIAID Schwartz
SAP/Sh2d1A Knockout	B6.129-Sh2d1atm1Pls	8424	Immunology	NIAID Schwartz

This project has been funded in whole or in part with Federal funds from the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, under Contract No. HHSN272201200029C.

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Taconic Emerging Models

Deleter Strains models
Model Name	Nomenclature	Taconic Model Number
Cre-ERT2	C57BL/6NTac-Gt(ROSA)26Sortm9(Cre/ESR1)Arte	10471
Cre Deleter	Gt(ROSA)26Sortm16(Cre)Arte	6467
Flp Deleter	Tg(CAG-Flpe)2Arte	7089

KinaseSwitch models
Model Name	Background	Taconic Model Number	Field of Application
Btk	C57BL/6	9723	Kinase studies, immunology, oncology
EphB4	C57BL/6	7742	Kinase studies, neuroscience, oncology
Pdgfr-β	C57BL/6	9070	Kinase studies, diabetes, oncology
Rps6kb1	C57BL/6	8026	Kinase studies, neuroscience, metabolic diseases, oncology

Other Taconic Emerging Models
Model Name	Nomenclature	Taconic Model Number
B6 Albino A++	C57BL/6NTac-Atm1.1Arte Tyrtm1Arte	11227
HRN™ nude	CrTac:NCr-Portm1Wolf Foxn1nu Tg(Alb-cre)21Mgn	9066

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Taconic tADMET™ Models

Learn more about the Taconic tADMET™ program

Model Name	Nomenclature	Taconic Model Number	Field of Application
Pxr-Car Knockout Mouse	C57BL/6-Nr1i2tm3Arte Nr1i3tm1.1Arte	8222	ADMET
Humanized PXR-CAR Mouse	C57BL/6-Nr1i2tm1(NR1I2)Arte Nr1i3tm1(NR1I3)Arte	8223	ADMET
Cyp3a (7-gene) Knockout Mouse	C57BL/6NTac-Del(5Cyp3a57-Cyp3a59)1Arte	8841	ADMET
Humanized CYP3A4/3A7 Mouse	C57BL/6-Del(5Cyp3a57-Cyp3a59)1Artetm1(CYP3A4-CYP3A7)Arte	8842	ADMET
Humanized Gut CYP3A4 Mouse	FVB.129P2-Cyp3a13tm1Ahs Del(5Cyp3a57-Cyp3a59)1Ahs Tg(Vil1-CYP3A4)1Ahs	9047	ADMET
Humanized Liver CYP3A4 Mouse	FVB.129P2-Cyp3a13tm1Ahs Del(5Cyp3a57-Cyp3a59)1Ahs Tg(APOE-CYP3A4)A1Ahs	9048	ADMET
Humanized Liver & Gut CYP3A4 Mouse	FVB.129P2-Cyp3a13tm1Ahs Del(5Cyp3a57-Cyp3a59)1Ahs Tg(Vil1-CYP3A4)1Ahs Tg(APOE-CYP3A4)A1Ahs	9049	ADMET
Pxr Knockout Mouse	C57BL/6-Nr1i2tm3Arte	9100	ADMET
Humanized CAR Mouse	C57BL/6-Nr1i3tm1(NR1I3)Arte	9101	ADMET
Car Knockout Mouse	C57BL/6-Nr1i3tm1.1Arte	9103	ADMET
Humanized PXR Mouse	C57BL/6-Nr1i2tm1(NR1I2)Arte	9104	ADMET
Humanized AHR Mouse	C57BL/6-Ahrtm1.1(AHR)Arte	9165	ADMET
Ahr Knockout Mouse	C57BL/6-Ahrtm1.2Arte	9166	ADMET
Cyp2c Knock Out Mouse	B6-Cyp2ctm1104Arte	9177	ADMET
Cyp2d Knockout Mouse	C57BL/6-Del(15Cyp2d22-Cyp2d26)1Arte	9178	ADMET
Humanized MRP2 Mouse	C57BL/6-Abcc2tm1(ABCC2)Arte	9179	ADMET
Pxr-Car-Ahr Knockout Mouse	C57BL/6-Nr1i3tm1.1Arte Ahrtm1.2Arte Nr1i2tm3Arte	11583	ADMET
Humanized CYP2D6 Mouse	C57BL/6-Is(15CYP2D6;Del15Cyp2d22-Cyp2d26)3Arte	11584	ADMET
Humanized PXR-CAR-CYP3A4/3A7 Mouse	C57BL/6-Nr1i3tm1(NR1I3)Arte Is(5CYP3A4-CYP3A7;Del5Cyp3a57-Cyp3a59)2Arte Nr1i2tm1(NR1I2)Arte	11585	ADMET
Humanized Liver CYP2C9		11746	ADMET

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Central Institute for Experimental Animals and In-Vivo Science International Sponsored Emerging Model

Model Name	Nomenclature	Taconic Model Number	Field of Application	Sponsoring Institution & Investigator
CIEA NOG mouse®	NOD.Cg-Prkdcscid Il2rgtm1Sug/JicTac	NOG	Oncology, Infectious Disease, Immunology, Humanization	Central Institute of Experimental Animals and In-Vivo Science International
CIEA BRG mouse	C.Cg-Rag2tm1Fwa Il2rgtm1Sug/JicTac	11503	Oncology, Infectious Disease, Immunology, Humanization	Central Institute of Experimental Animals and In-Vivo Science International

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Ludwig Institute Sponsored Emerging Model

Model Name	Nomenclature	Taconic Model Number	Field of Application	Sponsoring Institution & Investigator
TNFtm1	B6.129	1921		Ludwig Institute Ritter

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The ALS Association Sponsored Emerging Model

Model Name	Nomenclature	Taconic Model Number	Field of Application	Sponsoring Institution & Investigator
TgN(SOD1G93A)L26H	NTac:SD	2148	ALS Research	The ALS Association

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Emerging Models that are no longer available or have been replaced

Model Name	Nomenclature	Taconic Model Number	Disposition	Sponsoring Institution & Investigator
Rag2tm1 TgN(N15)	B6;129S6	421	No longer available	Dana Farber Reinherz
Rag2tm1 TgN(AND)	STOCK	422	No longer available	Dana Farber Reinherz
Igg3tm1	BALB/c	632	No longer available	Case Western Schreiber
Pik3r1tm1	C57BL/6 N7	725	No longer available. N12 model available from RIKEN	Keio University Koyasu
Pik3r1tm1	BALB/c N7	738	No longer available. N12 model available from RIKEN	Keio University Koyasu
Chromosome of interest: 4	NOD.B10-Idd9.1 Idd9.2 Idd9.3 N12	905	Available at Type 1 Diabetes Resource at the Jackson Laboratory	University of Cambridge
Chromosome of Interest 4	Idd9r11	907	No longer available	University of Cambridge Todd
Chromosome of interest 1		974	Available from the Type 1 Diabetes Resource at the Jackson Laboratory	University of Cambridge Todd
Pik3r1tm1	C57BL/6	1077	No longer available. Now available from RIKEN	Keio University Koyasu
Pik3r1tm1	BALB/C	1078	No longer available. Now available from RIKEN	Keio University Koyasu
Chromosome of interest 1		1092	Available from the Type 1 Diabetes Resource at the Jackson Laboratory	University of Cambridge
NOD.B10-Idd5.1 Idd5.2 Idd5.3		1094	May be available from the Type I Diabetes Resource at the Jackson Laboratory	University of Cambridge
Idd54467	NOD.B6	1095	May be available from the Type I Diabetes Resource at the Jackson Laboratory	University of Cambridge Todd
NOD.B6-Idd3		1098	May be available from the Type I Diabetes Resource at the Jackson Laboratory	University of Cambridge
<Idd10> <Idd18r2>	NOD.B6	1101	No longer available	University of Cambridge
Chromosome of Interest 4	<Idd9r28>	1104	Now available as Model 905	University of Cambridge Todd
Chromosome of Interest 4	<Idd9r11>	1105	May be available from the Type I Diabetes Resource at the Jackson Laboratory	University of Cambridge Todd
NOD.B10-Idd9.3 line 1106	NOD.B10-Idd9.3 N14	1106	Available from the Type 1 Diabetes Resource at the Jackson Laboratory	University of Cambridge
Chromosome of interest 17	<H2g7>	1107	Available from the Type 1 Diabetes Resource at the Jackson Laboratory	University of Cambridge
17	<H2b>	1108	Available from the Type 1 Diabetes Resource at the Jackson Laboratory	University of Cambridge
H2h4	NOD.B10	1109	Available from the Type 1 Diabetes Resource at the Jackson Laboratory	University of Cambridge Todd
NOD.B6-Idd3 Idd17 Idd10 Idd18 B10-Idd9 line 1112	NOD.B6-Idd3 Idd17 Idd10 Idd18 B10-Idd9 N6	1112	This line has been discontinued. If you have long term needs for this model, please set up a breeding colony, either at Taconic or at your own facility. Contact us immediately to purchase the necessary breeding animals. To be available from the Type 1 Diabetes Resource at the Jackson Laboratory.	Univeristy of Cambridge
Idd3 and Idd5	NOD.B6	1111 1591	No longer available	University of Cambridge Todd
TgN(APPSWE) 2576	B6;SJL	1349	Available as Commercial Model 1349	Mayo Clinic Stoddard
TgN(HO-1-luc)	FVB	1514-M	No longer available	Xenogen Campbell
Abbtm1 Tlr4<Lps-del>Sic11a1<a>	STOCK	1517	No longer available	Kansas State University Chapes
Chromosome of interest: 3	NOD.B6-Idd3 Idd10 Idd18 N12	1538	Available at Type 1 Diabetes Resource at the Jackson Laboratory	University of Cambridge
Chromosome of interest: 4	NOD.B10-Idd11 Idd9.1 N12	1565	Available at Type 1 Diabetes Resource at the Jackson Laboratory	University of Cambridge
NOD.B10-Idd9.2		1566	May be available from the Type I Diabetes Resource at the Jackson Laboratory	University of Cambridge
1 & 3	<Idd3/5> R450/467	1573	No longer available	University of Cambridge
TgN(iNOS-Luc)X-xen	FVB	1582	No longer available	Caliper Life Sciences
Rag2tm1 TgN(OT-II.2)	C57BL/6	1896	In development as Taconic Transgenic Model Rag2/OT-II. Sign up to receive colony updates.	Keio University Koyasu
NOD.B10-Idd5.1		2193	May be available from the Type I Diabetes Resource at the Jackson Laboratory	University of Cambridge
Rag2tm1 TgN(OT-I.1)	C57BL/6	2334	Available now as Taconic Transgenic Model Rag2/OT-I.	Keio University Koyasu
Chromosome of interest: 1	NOD.B10-Idd5.1 N16	2574	No longer available	University of Cambridge
BALB/c-plgRtm1	BALB/c	3767	No Longer Available	Albany Medical College Metzger
C57BL/6-plgRtm1	C57BL/6	3768	No Longer Available	Albany Medical College Metzger
Rag2 Knockout/Transgenic LCMV-P14 T Cell Receptor	B10;B6-Rag2tm1Fwa Tg(TcrLCMV)327Sdz	4113	Available now as Rag2 Knockout/Transgenic LCMV-P14 T Cell Receptor.	NIAID Schwartz
TgN(Cd-4Cre)	STOCK N2	4214	Now available at N9 Model 4196-M	NIAID Schwartz
p47 phox Knockout	B6.129S2-Ncf1tm1Shl N14	4227	No longer available	NIAID Schwartz
Ptgs-1tm1	B6;129P2	5001	Now available as Commercial Model 2180	NIEHS Langenbach
Ptgs-2tm1	B6;129P2	5002	Now available as Commercial Model 2181	NIEHS Langenbach
NOD.B-Idd5.1 Idd5.2 Idd5.3 Idd3		6109	May be available from the Type I Diabetes Resource at the Jackson Laboratory	University of Cambridge
NOD.B6-Ptprcb		6908	May be available from the Type I Diabetes Resource at the Jackson Laboratory	University of Cambridge
Type 1 Diabetes	NOD.B6-Idd10 Idd18	7754	Available at Type 1 Diabetes Resource at the Jackson Laboratory	University of Cambridge
T2DN	T2DN/Mcwi	7937	Diabetic Nephropathy	PhysioGenix: Dahly-Vernon
FatRat™	WH-Mc4rfat1Hubr	10682/11203	No longer available through Taconic	Transposagen Biopharma, Jack Crawford

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