Improving Drug Discovery

Biomedical researchers depend on sophisticated tools to accelerate drug development, reduce costs, and speed time-to-market with new and promising therapies. To achieve those goals, the world's leading pharmaceutical and biomedical companies, government agencies and academic institutions turn to Taconic.

Taconic is a leading provider of life sciences solutions to researchers worldwide, offering innovative animal models and scientific services that facilitate in vivo studies and advance drug discovery. Our solutions enable investigators to obtain reliable data early in the development cycle - reducing costs, accelerating time-to-market, and creating a strong competitive advantage.

A broad portfolio of relevant animal models and services - combined with unrivaled scientific expertise and a global footprint - enables Taconic to deliver the highest quality solutions quickly and reliably. Through seven breeding facilities and three service labs in the U.S. and Europe, more than 1,000 Taconic scientists and specialists demonstrate their commitment to technological innovation every day.

Taconic's industry leading portfolio of solutions includes:

• Custom model generation services that provide easy access to precisely defined models to suit your specific research project, using advanced technologies such as pronuclear microinjection, targeted gene mutation and targeted gene replacement



• Extensive animal model repositories, including the Taconic Transgenic Model™ portfolio of in-licensed transgenics, a Knockout Repository of 3,600+ mouse lines, and the Emerging Models portfolio of investigator-sponsored models



• transADMET™ models that yield far greater predictability of ADMET in man and improve the safety assessment of drug candidates by knocking out key murine genes or replacing them with their human counterparts



• In vivo Compound Profile program, a powerful in vivo compound profiling service that accelerates drug discovery by assessing lead compound efficacy and identifying potential side effects early in the cycle



• PhenoTac™, a proprietary phenotyping solution that saves substantial time and money by yielding more data, significantly faster, and with far fewer animals than traditional options (available only from Taconic)



• Light-producing transgenic models and imaging studies that use novel bioluminescent technology to greatly enhance the study of inflammation, oncology, metabolic disease, and drug metabolism/toxicology



• Contract research solutions that help you complete pre-clinical studies rapidly and cost-effectively, leveraging our expertise in areas such as diet administration, neurodegeneration, compound administration and tumor modeling



• Custom breeding solutions customized to your specific needs and designed to help you achieve your research objectives, by providing the right models quickly, cost-effectively and in the volume your research demands



• Surgical services including cannulations and implants, customized procedures, and the creation of surgical models of disease, all performed by highly trained in-house surgical technicians



• Testing services that use the most advanced technology to determine the precise genetic characterization of your model and monitor animal health status



• Health monitoring services through our proprietary Taconic International Health Monitoring System™, which meets or exceeds the animal health guidelines of virtually all research institutions