Laboratory rats with a single gene trap insertion created using mobile DNA technology.
The TKO™ Rat Repository of ~90 knockout* rat lines provides researchers worldwide with unparalleled access to fully-licensed, newly available knockout rat models. Our repository offers the scientific community immediate access to highly valuable research tools that rapidly accelerate the drug discovery and development processes.
| Catalog Number | Gene | Application |
|---|---|---|
| TK0018 | Cyp7b1 | ADMET |
| TK0080 | Slc7a11 | ADMET, oncology |
| TK0079 | Slc16a12 | ADMET, ocular disorders |
| TK0020 | Dcc | Oncology |
| TK0035 | Kcnh7 | Autoimmune disorders |
| TK0056 | Myo9a | Hydrocephalus model |
*Please note: all TKO™ Rat lines are predicted to be knockouts, but complete knockout has not been confirmed by Western blot in most cases.