"The construction and distribution of the inducible tafazzin knockdown mouse model of Barth syndrome generated by Taconic and supported by the Barth Syndrome Foundation (BSF) has been a vital tool in advancing research about this rare disease. Two relatively quick publications (Acehan et al. , 2010, and Soutek et al. , 2011) and a recent a follow-up paper (Phoon et al., 2012) detail the amazing physiological and pathological parallels between this mouse model and the human disorder. Within just a few years since its emergence, this mouse model of a rare human disorder is used by over 50% of the applicants to the BSF Research Grant Program to obtain funding for their work. Initial efforts by several laboratories to make a tafazzin knockout mouse model of Barth syndrome were unsuccessful, however the shRNA method along with the proprietary technology available at Taconic has produced a truly useful resource for in vivo, ex vivo, and drug-discovery investigations."
-Barth Syndrome Foundation, Inc.
"Taconic's strengths are the quality of its animals, on-time delivery and fantastic customer service. The lack of Nnt mutation is critical to us and another reason we use Taconic models."
-Duke University Medical Center
"We're always pleased with the traditional and emerging models Taconic provides for our biomedical research. We've found its B6 model to be much cleaner than other suppliers."
"Taconic offers our investigators very good product availability, communication, customer service and pricing. It's our preferred source for the catheterized animals we receive monthly."
-Sanford Burnham Medical Research
"Taconic offers a very good repository of knockout mouse models. It's the first source we go to for knockouts for our research on brain disorders, including epilepsy and Alzheimer's."
-University of Minnesota
"Your punctual communication, scientific rigor, attention to detail, and overall delightful demeanor have been so appreciated."
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