Human immune system NOG mice - non oncology applications

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Agenda:
Humanized pharmacological assays are representative of specific mechanisms of action resulting from interactions between human cells, and can produce measurable and translational readouts for a large panel of applications. In this webinar, attendees learned how human immune system mice are unequaled tools for acquiring data on the effects of a drug on the human immune system and correlated diseases: autoimmune diseases, acute and chronic inflammation, allergy and infectious diseases. Caroline Mignard, provided an overview of human and mouse immunology, and highlighted the potential of human immune system NOG mice through selected case studies. The webinar went into detail about the process developed by Taconic and Oncodesign to generate standard and robust delivery of human immune system engrafted mice cohorts.

More about the Caroline Mignard, Ph.D.:

After obtaining a Ph.D in Biology from the University of Strasbourg in France, Caroline Mignard worked as preclinical project leader in a Contract Research Organization (CRO) in Strasbourg for 4 years. She then joined Oncodesign in 2004 as a Study Director in preclinical research, and she is now the Director of Oncodesign's Biological and Chemical Resource Center (BCRC). Caroline continues to supervise experimental studies for Oncodesign's customers, particularly involved in studies based on mice reconstituted with human immune system or grafted with patient primary tumors (PDX).

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