| Model No. | Nomenclature | Genotype |
|---|---|---|
| 6510 | B6;129S6-Gabra5tm1.2 twr | Inquire for genotype |
Gabra5 - Model 6510 - KO
View:
Select One
- Description
- Price & Licensing
- Overview
- Genetics
- Guides & Publications
- Transit, Housing & Welfare
Overview
Nomenclature: B6;129S6-Gabra5tm1.2 twr
- The targeting vector has been generated using 129SvEv DNA and transfected into 129SvEv ES cell line.
- Gabra5 exons 2-4 were partially deleted by the neomycin resistance cassette, which is flanked by loxP sites.
- Chimeric mice were produced and germ line transmission achieved.
- The neomycin resistance gene has not been deleted in the constitutive KO mice.
- Deletion of parts of exons 2 and 4 and complete deletion of exon 3 should result in loss of function of the Gabra5 gene by deleting functional domains of the protein.
- Gabra5 constitutive KO mice are in a mixed C57BL/6-129SvEv genetic background.
- See N. Collinson et al, The Journal of Neuroscience 22, 5572-5580, 2002, for further details.
Availability
Cryopreserved at TaconicSource: Merck Research Laboratories
This model is cryopreserved and available for recovery. Models can typically be recovered and delivered to customers within 14-16 weeks after order receipt. Purchase of this model includes perpetual use rights and a deliverable of four mutant animals at the Murine Pathogen Free™ health standard along with a genotyping protocol. For models which include a recombinase gene or multiple alleles, all alleles will be provided, but individual animals may not contain all mutant alleles.
Taconic’s Colony Management experts can design a plan to grow your colony faster.
Guides & Publications
Transit, Housing & Welfare
Need more info? Click the live chat button or Contact Us
- Licensing
- Pricing
- Select my Health Standard
- Get Custom Pricing Guide
Gabra5 - Model 6510 - KO
Customers may purchase this model by signing the appropriate Terms of Sale (below) and providing a PO.
The GEM Collection Commercial and Academic Terms of Sale grant perpetual use rights.
| Item | Commercial | Nonprofit |
| Cryopreserved Model | $32,500 | $5,500 |
| Item | Commercial | Nonprofit |
| Cryopreserved Model | €29.500 | €5.005 |
Cryopreserved models are invoiced upon shipment of recovered animals. Once orders are placed, the full purchase price will be applied if the order is canceled. For orders greater than 4 animals, please contact Taconic for options.
Fees for Taconic Transit Cages™ and freight are in addition to the price above.
Select my Health Standard
Need help choosing the right Taconic Biosciences health standard for your research?
Use the Health Standard Selector to enter your exclusion list. The tool will tell you which health standards meet your requirements.
Get custom pricing guide
Schedule A Scientific Consultation
Speak with a PhD-level Field Application Scientist who can help you select the most appropriate model and maximize your experimental success.
