Neurodegenerative Diseases and the Microbiome: Lessons Learned from Mouse Models

It is without a doubt that research into the microbiome has been rapidly increasing in the last ten years. One of the specific fields involved is the field of neurology, which is focused on investigating how the intestinal microbiome can influence the progression of neurodegenerative diseases. A recent article published in The Journal of Precision Medicine cites Taconic Biosciences' Dr. Alexander Maue as stating that "it appears that shifts from a healthy, normal microbiome composition to an altered form, defined as dysbiosis, can disrupt the gut-brain axis, is associated with disease states and may be an early event in pathogenesis." Additionally, Dr. maue continues on to discuss how the research mouse has been essential for studying the gut-brain connection and progression of neurological disease:

Dr. Alexander Maue"Humans play host to a community of trillions of microorganisms collectively termed the microbiome. Investigations into the microbiome and how it impacts human health represent one of the most rapidly growing fields of study. A simple Pubmed search for "'microbiome" demonstrates a greater than 700% increase in the number of publications from 2010 to 2017. During this time period, key links between the microbiome and various conditions and disease states have been demonstrated including, but not limited to, cancer progression and treatment, metabolic disorders and inflammatory bowel disease."
Read the complete article at: theJournalofPrecisionMedicine.com