One of the key challenges of drug development is to better predict drug responses in humans. This white paper offers insights on how such challenges are being overcome by a portfolio of pre-validated in vivo and in vitro tools.These tools offer solutions along various stages of the drug development pipeline and help improve drug candidate selection, increase clinical success rates, and reduce costs. Applications include use in early in vitro screening, preclinical in vivo studies, and in clinical phases.
Taconic Biosciences' recent White Paper Challenges and Prospects in Predicting the ADME and Toxicity Characteristics of Drugs in Humans covers the following topics:
- Precision Research Models for studying drug metabolism, disposition, and toxicity.
- FDA accepted mouse models for short-term carcinogenicity studies.
