The Translational Scientist converses with Taconic Biosciences' Portfolio Director Dr. John Couse about pre-clinical mouse models, specifically "how the shifting techniques and technologies in bioscience affect — and are affected by — mouse models":
"The pre-clinical mouse model is an essential part of many translational medicine journeys, providing preliminary efficacy results that often determine if treatments are able to make the leap into clinical trials. With the growing availability of tools and techniques for genetic recombination, mouse models appear to allow access to increasingly relevant results... or do they? Some researchers argue that alternatives to animal models are overdue, others believe that they're still the best pre-clinical option."
Read* the complete article at: TheTranslationalScientist.com
"The pre-clinical mouse model is an essential part of many translational medicine journeys, providing preliminary efficacy results that often determine if treatments are able to make the leap into clinical trials. With the growing availability of tools and techniques for genetic recombination, mouse models appear to allow access to increasingly relevant results... or do they? Some researchers argue that alternatives to animal models are overdue, others believe that they're still the best pre-clinical option."