March 16-20, 2025 |  Orange County Convention Center | Orlando, Florida 

2025 SOT Annual Meeting and ToxExpo

Taconic Biosciences is pleased to attend the 2025 SOT Annual Meeting and ToxExpo to support advancing science and increasing the impact of toxicology.

Complete the form below to request a meeting to discuss your project needs with a scientist.

We partner with researchers to facilitate toxicology research and accelerate discovery while maintaining efficient resource use. Using the right animal model is key to a study's success. Speak with a representative to determine how Taconic scientists support researchers with model selection and custom model generation.

Don't miss our partner, the Central Institute of Experimental Medicine's (CIEM) poster sessions at SOT this year, featuring insightful presentations on the TK NOG mouse and two compelling posters on the rasH2™ mouse.

Key Information:

  • When: March 16-20, 2025
  • What: Three poster presentations: see details below
  • Time: See details below
  • Where: Orange County Convention Center - West Concourse, 9800 International Drive, Orlando, FL

rasH2™ mouse: The gold standard for carcinogenicity testing in vivo

Assess Your Small Molecule Drug for Carcinogenicity Faster and at a Lower Cost with the Taconic Biosciences rasH2™ transgenic mouse model. Learn more about this rodent model, used for testing and research.

View the rasH2™ mouse
rasH2™ mouse

Request a Meeting with Taconic at SOT

Poster Sessions

Monday, March 17 | 1:45 pm - 4:15 pm 

Animal Models

3008: Poster Board - A109: N-methyl-N-nitrosourea-induced forestomach neoplastic lesions are formed in rasH2™ mice at 13 weeks after a single intra-abdominal injection.

Authors: T. Numano1, R. Inoue1, C. Nishime1, M. Yasuda1, Y. Kamai1, M. Mochizuki1, K. Kawai1, T. Miyake2, I. Owada2, T. Yamamoto1, and M. Suzuki1. 1Central Institute for Experimental Medicine and Life Science, Kawasaki-shi, Japan; and 2CLEA Japan, Inc., Fujinomiya-shi, Japan.

Wednesday, March 19 | 9:15 am -11:45 am 

Liver: In Vitro

4506: Poster Board - G339: Utility of HepaSH cells derived from chimeric mice with humanized liver for in vitro assessment of DILI risk in humans.

Authors: S. Uehara1, H. Kawagishi2, X. Liu2, Y. Sakamoto2, N. Yoneda1, Y. Higuchi1, H. Suemizu1, and Y. Kanda2. 1Central Institute for Experimental Medicine and Life Science, Kawasaki, Japan; and 2National Institute of Health Sciences, Kawasaki, Japan.

Wednesday, March 19 | 1:45 pm - 4:15 pm 

Carcinogenesis

4678: Poster Board - J516: RasH2™ mouse-derived esophageal organoids show higher susceptibilities to 4-NQO without S9 than those with S9 in an ex vivo carcinogenesis model.

Authors: T. Imai, M. Akeyoshi, C. Nishime, M. Mochizuki, K. Kawai, T. Yamamoto, and M. Suzuki. Central Institute for Experimental Medicine and Life Science, Kawasaki, Japan.