NOG Portfolio

A unique collection of superimmunodeficient mouse models with broad applications built upon the CIEA NOG mouse®.

Albino mouse standing

Featured Resource

Taconic Biosciences Receives 2024 Novel Product Award at Merck Technology Symposium

We are pleased to announce that the cutting-edge FcResolv® NOG portfolio has been recognized for its key applications in driving advancements in preclinical antibody-based drug discovery.

award

The Taconic NOG Portfolio of superimmunodeficient and humanized immune system mice

The NOG mouse offers many advantages over standard nude and scid strains, particularly for engraftment of challenging cell lines, patient-derived xenografts, and immune system humanization.

NOG EXL

Explore the Collection

The superimmunodeficient NOG mouse is the base of a flexible platform which includes a variety of next-generation models which have specific utility as well as several different types of humanized immune system (HIS) models.

CIEA NOG mouse®

This immunodeficient mouse model lacks mature T, B, and NK cells, displays reduced complement activity, has dysfunctional macrophages and dendritic cells, & more.
CIEA NOG Mouse

FcResolv™ NOG Portfolio

The FcResolv NOG models are the first and only super immunodeficient mice with knockout of murine Fc gamma receptors to improve accuracy of results when assessing antibody-based therapeutics
monoclonal antibody graphic

Next-Generation NOG Models

Further genetic modifications have been carried out on the CIEA NOG mouse to develop next-generation models to improve experimental outcomes in a wide range of applications.
second gen NOG mice post-engraftment chart

Humanized Immune System Mice

Taconic Biosciences uniquely combines access to a robust humanized immune system (HIS) mouse model portfolio with engraftment expertise to maximize experimental success.
diagram of mouse and human immune cells

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If you need immediate assistance, please contact Customer Service:

Taconic Corporate Offices

Email: info@taconic.com
Phone: +1 (518) 697-3900
273 Hover Ave., Germantown, NY 12526

North American Customer Service

Email: info@taconic.com
Phone: +1 (518) 697-3915 
Toll-free:  +1 (888) 822-6642

Hours: (Monday - Friday): 7 a.m. - 6 p.m. ET

European Customer Service

Email: info@taconic.com
Phone (Europe and Denmark): +45 70 23 04 05 
Phone (Germany): +49 214 50 68 023 
Hours: (Monday - Friday): 7 a.m. - 5 p.m. CET

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