B6JBom

B6JBom Inbred Mouse Model
  • Live
  • Mouse
  • Male & Female Available
  • Black
  • Available for direct purchase by CRO
Model No.NomenclatureGenotype
B6JBOM-F C57BL/6JBomTac
B6JBOM-M C57BL/6JBomTac
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Overview

Nomenclature: C57BL/6JBomTac

  • Slightly smaller than the C57BL/6NTac, this subline is extensively used in the research applications of oncology, immunology, and toxicology

Origin

The Black 6 Bom inbred model was developed by Little et al. Hall received stock. Jackson Laboratory received stock from Hall in 1948. Zentralinstitut für Versuchsteirzucht, Hannover Germany (Han) received stock in 1971. M&B A/S (now Taconic Europe) received stock at F141 in 1988. The mice were derived by embryo transfer in January 2000.

The Taconic US foundation colony was at F156 + 35 in 2005.

Genetics

Species:Mouse
Strain Type:Inbred
Coat Color:Black
Coat Color Loci: a
Genetic Background:C57BL/6
Coat Color Loci: a

Other Genetic Notes:

  • Strain Profile: Akp1a, Akp2b, Anpepa, Car2a, Es1a, Es2b, Es3a, Es5b, Es9a, H6pd1a, Gpi1b, Got2b, Hbbs, Idh1a, Ldr1a, Ldr2a, Mod1b, Mup1b, Pep3a, Pgm1a, Trfb
  • Immunology: H2b
  • The C57BL/6JBomTac substrain carries a mutation in the Y chromosome. More information is available in the following two papers: MacBride MM et al. Mild reproductive impact of a Y chromosome deletion on a C57BL/6J substrain. Mamm Genome 2017; 28(5-6):155-165 and Fischer M et al. Large deletion on the Y-chromosome long arm (Yq) of C57BL/6JBomTac inbred mice. Mamm Genome 2017; 28(1-2):31-37.

Applications & Therapeutic Areas

  • ADMET
  • Inflammatory Bowel Disease
  • Metabolic Disease
  • Microbiome
  • Model Generation Solutions
  • Neuroscience
  • Oncology & Immuno-Oncology
  • Ophthalmology
  • "Parkinsons Disease"
  • Psychiatric Disorders
  • Vaccine Research
  • "Alzheimers Disease"
  • Autoimmune Disease
  • Cardiovascular Disease
  • Diabetes
  • Epilepsy
  • Immunology
  • Infectious Disease
  • Inflammation

Transit, Housing & Welfare

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B6JBOM males at 7+ weeks of age are packed as cagemates, without recombination of animals from different cages into a single Taconic Transit Cage (TTC). We recommend that customers do NOT recombine 7+ week old B6JBOM males from different Taconic Transit Cages into the same cage at or after unpacking.

Packing Practices

Taconic standard practice is to recombine animals of different home cages and/or ages from a single model and sex during packing, except in specific cases where Taconic's animal welfare policy prohibits recombination due to aggression or other concerns.  When an order is fulfilled with animals from more than one week of birth, this standard practice results in animals from a range of birth weeks packed together in a single TTC. When an order is fulfilled with animals from genotyped models, this standard practice results in animals from different home cages packed together in a single TTC.

Customers who wish to keep animals from different weeks of birth separated should place orders with the special instruction "Divide and label by age."  Note that this special request can result in increased costs for additional Taconic Transit Cages, dividers and/or freight charges.

Taconic discourages other types of custom packing requests as they can have a negative impact on animal welfare. Learn more.

Surgical Models and Services

mouse

Data

Average litter size: 6
  • They have a high preference for ethanol and morphine, and are susceptible to streptozotocin-induced diabetes. This strain is relatively resistant to mycobacterium leprae murium infection.

Taconic mice do not carry the Nnt Mutation

For some applications, weight may be critical. For orders where weight is critical, please place orders by weight, not by age. Taconic can accept orders by weight for this model for mice sourced from European colonies only. A minimum 3 gram span is required. All weights are weights at time of packing. Mice and rats can lose weight in transit. Orders for specific weight spans will be assessed a nominal fee.

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n= 80 per sex at MPF health standard from EU production colonies. Data collected 2014-15.
High and Low represent mean +/- 1 standard deviation.
Based on sample size the charts above represents ~65% of the population.
All growth curves represent animals housed in our barriers, at our standard density and fed NIH31-M diet. Variations at customer facilities will alter expected growth curves. Growth charts are provided only as a guide, if a specific weight criteria is needed please order animals by weight.


Customize this chart by clicking the legend elements.

Licensing

Terms of Sale and Use for B6JBOM

These models are sold subject to Taconic's Terms and Conditions for Taconic's Models, Products and Services

Pricing - USD

Murine Pathogen Free (MPF) Health Standard

B6JBOM Female

B6JBOM-F

Age in WeeksQuantity 1 - 999
3 to 4$136.00
5 to 7$151.00
8 to 9$163.00

Specialized Inventory

B6JBOM-RFQuantity 1 - 199
Retired Female Breeder$170.00

Specialized Inventory

B6JBOM-UPQuantity 1 - 199
Untimed Pregnant Female$850.00

*Untimed pregnant requests are filled with late gestation pregnant females. Pups may be delivered in transit.

B6JBOM Male

B6JBOM-M

Age in WeeksQuantity 1 - 999
3 to 4$136.00
5 to 7$151.00
8 to 9$163.00

Specialized Inventory

B6JBOM-RMQuantity 1 - 199
Retired Male Breeder$170.00

Pricing - EUR

Murine Pathogen Free (MPF) Health Standard

B6JBOM Female

B6JBOM-F

Age in WeeksQuantity 1 - 999
3 to 4€33,00
5 to 6€35,00
7 to 8€37,00
9 to 10€40,00
11 to 12€44,00

Specialized Inventory

B6JBOM-FLQuantity 1 - 199
Female With Litter€328,00

Specialized Inventory

B6JBOM-RFQuantity 1 - 199
Retired Female Breeder€42,00

Specialized Inventory

B6JBOM-TPQuantity 1 - 999
Timed Pregnant Female€416,00

Specialized Inventory

B6JBOM-UPQuantity 1 - 199
Untimed Pregnant Female€277,00

*Untimed pregnant requests are filled with late gestation pregnant females. Pups may be delivered in transit.

B6JBOM Male

B6JBOM-M

Age in WeeksQuantity 1 - 999
3 to 4€33,00
5 to 6€35,00
7 to 8€37,00
9 to 10€40,00
11 to 12€44,00

Specialized Inventory

B6JBOM-RMQuantity 1 - 199
Retired Male Breeder€42,00

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  • Evaluate a specific model strain, before making any financial investment
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