BALB/c Bom

BALB/c Bom Inbred Mouse Model
  • Live
  • Mouse
  • Male & Female Available
  • Albino
  • Available for direct purchase by CRO
Model No.NomenclatureGenotype
BALJBO-F BALB/cJBomTac
BALJBO-M BALB/cJBomTac
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Overview

Nomenclature: BALB/cJBomTac

  • This subline is the most widely-used for the production of monoclonal antibodies by hybridoma technique
  • Males are non-aggressive and easy to handle

Origin

The Laboratory Animal Center (Lac) received the BALB/c Bom inbred model from the Jackson Laboratory in 1955. The Zentralinstitut für Versuchstierzucht in Hannover Germany (Han) received stock from Lac. M&B A/S (now Taconic Europe) received stock at F68 from Han in 1987. The Taconic foundation colony was at F83 + 17 in 2000.

Genetics

Species:Mouse
Strain Type:Inbred
Coat Color:Albino
Genetic Background:BALB/c

Other Genetic Notes:

  • Strain Profile: Akp1b, Akp2a, Anpepb, Car2b, Es1b, Es2b, Es3a, Es5b, Es9a, H6pd1b, Gpi1a, Got2b, Hbbd, Idh1a, Ldr1a, Ldr2a, Mod1a, Mup1a, Pep3a, Pgm1a, Trfb
  • Immunology: H2d

Guides & Publications

Applications & Therapeutic Areas

  • ADMET
  • Inflammatory Bowel Disease
  • Metabolic Disease
  • Microbiome
  • Model Generation Solutions
  • Neuroscience
  • Oncology & Immuno-Oncology
  • Ophthalmology
  • "Parkinsons Disease"
  • Psychiatric Disorders
  • Vaccine Research
  • "Alzheimers Disease"
  • Autoimmune Disease
  • Cardiovascular Disease
  • Diabetes
  • Epilepsy
  • Immunology
  • Infectious Disease
  • Inflammation

Transit, Housing & Welfare

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Packing Practices

Taconic standard practice is to recombine animals of different home cages and/or ages from a single model and sex during packing, except in specific cases where Taconic's animal welfare policy prohibits recombination due to aggression or other concerns.  When an order is fulfilled with animals from more than one week of birth, this standard practice results in animals from a range of birth weeks packed together in a single TTC. When an order is fulfilled with animals from genotyped models, this standard practice results in animals from different home cages packed together in a single TTC.

Customers who wish to keep animals from different weeks of birth separated should place orders with the special instruction "Divide and label by age."  Note that this special request can result in increased costs for additional Taconic Transit Cages, dividers and/or freight charges.

Taconic discourages other types of custom packing requests as they can have a negative impact on animal welfare. Learn more.

Surgical Models and Services

mouse

Data

Average litter size: 8
  • Pathophysiology: Low mammary tumour incidence, but susceptible to MMTV. Heart lesions in older breeders and arteriosclerosis common. High levels of alpha-fetoprotein in adult mice (Olsson et al. 1977). Susceptible to induction of plasma cell tumors with mineral oil. Susceptible to chronic pneumonia. Large reticuloendothelial organs relative to body weight. Extremely sensitive to radiation. Resistant to insoniazid induced seizure.
  • Characteristics: Males of the Lac subline are non-aggressive (Festing 1986).
  • Application in Biomedical Research: Plasmacytomas induced by injection of mineral oil or pristane from the basis for the production of monoclonal antibodies by hybridoma technique (Furmanski & Rich 1982). BALB/cJ is widely used for this purpose. For antibody production in ascites, F1 hybrids of BALB/cJ and an outbred Swiss mouse (i.e. NMRI) may be advantageous (Broder & Tsang 1986).

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n= 40 per sex at MPF health standard from EU production colonies. Data collected 2014-15.
High and Low represent mean +/- 1 standard deviation.
Based on sample size the charts above represents ~60% of the population.
All growth curves represent animals housed in our barriers, at our standard density and fed NIH31-M diet. Variations at customer facilities will alter expected growth curves. Growth charts are provided only as a guide, if a specific weight criteria is needed please order animals by weight.


Customize this chart by clicking the legend elements.

Licensing

Terms of Sale and Use for BALB/C BOM

These models are sold subject to Taconic's Terms and Conditions for Taconic's Models, Products and Services

Pricing - USD

Murine Pathogen Free (MPF) Health Standard

BALJBO Female

BALJBO-F

Age in WeeksQuantity 1 - 999
3 to 4$27.00
5 to 7$38.00
8 to 9$47.00

Specialized Inventory

BALJBO-RFQuantity 1 - 999
Retired Female Breeder$48.00

Specialized Inventory

BALJBO-TPQuantity 1 - 999
Timed Pregnant Female$703.00

Specialized Inventory

BALJBO-UPQuantity 1 - 999
Untimed Pregnant Female$262.00

*Untimed pregnant requests are filled with late gestation pregnant females. Pups may be delivered in transit.

BALJBO Male

BALJBO-M

Age in WeeksQuantity 1 - 999
3 to 4$27.00
5 to 7$38.00
8 to 9$47.00

Specialized Inventory

BALJBO-RMQuantity 1 - 999
Retired Male Breeder$48.00

Pricing - EUR

Murine Pathogen Free (MPF) Health Standard

BALJBO Female

BALJBO-F

Age in WeeksQuantity 1 - 199Quantity 200 - 999
3 to 4€26,00€24,00
5 to 6€29,00€26,00
7 to 8€32,00€29,00
9 to 10€34,00€32,00

Specialized Inventory

BALJBO-FLQuantity 1 - 199
Female With Litter€258,00

Specialized Inventory

BALJBO-RFQuantity 1 - 199
Retired Female Breeder€34,00

Specialized Inventory

BALJBO-TPQuantity 1 - 999
Timed Pregnant Female€396,00

Specialized Inventory

BALJBO-UPQuantity 1 - 199
Untimed Pregnant Female€205,00

*Untimed pregnant requests are filled with late gestation pregnant females. Pups may be delivered in transit.

BALJBO Male

BALJBO-M

Age in WeeksQuantity 1 - 199Quantity 200 - 999
3 to 4€26,00€24,00
5 to 6€29,00€26,00
7 to 8€32,00€29,00
9 to 10€34,00€32,00

Specialized Inventory

BALJBO-RMQuantity 1 - 199
Retired Male Breeder€34,00

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