| Model No. | Nomenclature | Genotype |
|---|---|---|
| SW-F | Tac:SW | |
| SW-M | Tac:SW |
Swiss Webster
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Overview
Nomenclature: Tac:SW
- Extensively used for decades as an all-purpose stock for research and drug safety testing
- Often used as recipient mother in transgenic labs due to its superior nurturing ability
- Swiss Webster females (SW-F) are also ideal pseudopregnant recipients for embryo transfers of black and agouti mouse lines
Origin
Taconic received the Swiss Webster outbred model from the Rockefeller Institute through Rockland Farms, Inc. in 1940. The mice have been maintained as a closed colony since 1951. The mice were derived by caesarean from randomly chosen breeders and reintroduced into a Barrier Nucleus Expansion Colony in 1965-1969. The mice were derived by caesarean in 1983 from randomly chosen breeders from all Taconic's barrier units.
Genetics
Guides & Publications
Applications & Therapeutic Areas
- Safety Assessment
- Transgenic Model Generation Support
- Vaccine Research
Transit, Housing & Welfare
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Packing Practices
Taconic standard practice is to recombine animals of different home cages and/or ages from a single model and sex during packing, except in specific cases where Taconic's animal welfare policy prohibits recombination due to aggression or other concerns. When an order is fulfilled with animals from more than one week of birth, this standard practice results in animals from a range of birth weeks packed together in a single TTC. When an order is fulfilled with animals from genotyped models, this standard practice results in animals from different home cages packed together in a single TTC.
Customers who wish to keep animals from different weeks of birth separated should place orders with the special instruction "Divide and label by age." Note that this special request can result in increased costs for additional Taconic Transit Cages, dividers and/or freight charges.
Taconic discourages other types of custom packing requests as they can have a negative impact on animal welfare. Learn more.
Diet
- Services
Data
Average litter size: 11
Groups of virgin females at 8 weeks of age were mated with male retired breeders. Vaginal plugs were observed on days 1-4 following set up. The incidence rate of vaginal plug observations were:
| Day 1 | 6.9% |
| Day 2 | 8.3% |
| Day 3 | 26.2% |
| Day 4 | 4.8% |
The percentage of females found with plugs that were not, in fact, pregnant was less than 10%.
An analysis was made of 200 timed pregnant females to determine the length of gestation (plug observation date = day 1). The results are as follows:
| Day 18 | 2.5% |
| Day 19 | 29.0% |
| Day 20 | 50.0% |
| Day 21 | 11.5% |
| Day 22 | 6.0% |
| Day 23 | 1.5% |
Eight timed pregnant females were housed individually. The body weight of each pup in each litter was recorded and the average weight per pup calculated:
Pre-Weanling Body Weights in Grams | ||||
|---|---|---|---|---|
| # Pups in Litter | 8 | 10 | 11 | 13 |
| # of Litters Observed | 1 | 2 | 2 | 3 |
| Days of Age | ||||
| 1 | 1.63 | 1.50 | 1.55 | 1.36 |
| 2 | 1.77 | 1.60 | 1.70 | 1.46 |
| 5 | 3.30 | 2.71 | 3.04 | 2.40 |
| 8 | 5.36 | 4.21 | 4.62 | 3.75 |
| 10 | 6.52 | 5.30 | 5.61 | 4.77 |
| 12 | 7.51 | 6.07 | 6.21 | 5.55 |
| 15 | 8.75 | 7.10 | 7.23 | 6.31 |
| 17 | 9.16 | 7.49 | 7.32 | 6.63 |
| 19 | 9.95 | 8.39 | 8.28 | 7.06 |
| 21 | 12.27 | 10.30 | 10.23 | 9.95 |
- MPF Health Standard
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- MPF Health Standard
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- Licensing
- Pricing - USD
- Pricing - EUR
- Pricing - USD Nonprofit
- Pricing - EUR Nonprofit
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Licensing
Terms of Sale and Use for Swiss Webster
Germ Free Swiss Webster are sold subject to Taconic's Terms and Conditions for Taconic's Models, Products and Services and the following terms of use:- For-profit purchasers may not breed Germ Free Swiss Webster except to obtain embryos or fetuses for research use.
- Non-profit purchasers may breed Germ Free Swiss Webster for use in projects at purchaser's institution and on behalf of non-profit researchers only.
- Germ Free Swiss Webster, progeny and materials derived from them will not be distributed to third parties.
Pricing - USD
Murine Pathogen Free (MPF) Health Standard
SW Female
SW-F
| Age in Weeks | Quantity 1 - 999 |
| 3 to 4 | $16.00 |
| 5 to 6 | $18.00 |
| 7 to 8 | $20.00 |
| 9 to 10 | $21.00 |
| 11 to 12 | $26.00 |
Specialized Inventory
| SW-FL | Quantity 1 - 199 |
| Female With Litter | $176.00 |
Specialized Inventory
| SW-TP | Quantity 1 - 999 |
| Timed Pregnant Female | $168.00 |
Specialized Inventory
| SW-RF | Quantity 1 - 199 |
| Retired Female Breeder | $22.00 |
SW Male
SW-M
| Age in Weeks | Quantity 1 - 999 |
| 3 to 4 | $16.00 |
| 5 to 6 | $18.00 |
| 7 to 8 | $20.00 |
| 9 to 10 | $21.00 |
| 11 to 12 | $26.00 |
Specialized Inventory
| SW-RM | Quantity 1 - 199 |
| Retired Male Breeder | $23.00 |
Opportunist Free (OF) Health Standard
SW Female
SW-F
| Age in Weeks | Quantity 1 - 999 |
| 3 to 4 | $35.00 |
| 5 to 6 | $38.00 |
| 7 to 8 | $40.00 |
| 9 to 10 | $43.00 |
Specialized Inventory
| SW-FL | Quantity 1 - 199 |
| Female With Litter | $208.00 |
Specialized Inventory
| SW-TP | Quantity 1 - 999 |
| Timed Pregnant Female | $297.00 |
Specialized Inventory
| SW-UP | Quantity 1 - 199 |
| Untimed Pregnant Female | $209.00 |
*Untimed pregnant requests are filled with late gestation pregnant females. Pups may be delivered in transit.
SW Male
SW-M
| Age in Weeks | Quantity 1 - 999 |
| 3 to 4 | $35.00 |
| 5 to 6 | $38.00 |
| 7 to 8 | $40.00 |
| 9 to 10 | $43.00 |
Germ Free (GF) Health Standard
SW Female
SW-F
| Age in Weeks | Quantity 1 - 999 |
| 4 | $240.00 |
| 5 | $256.00 |
| 6 | $280.00 |
| 7 | $304.00 |
| 8 | $328.00 |
| 9 | $344.00 |
| 10 | $360.00 |
Specialized Inventory
| SW-UP | Quantity 1 - 199 |
| Untimed Pregnant Female | $1,994.00 |
*Untimed pregnant requests are filled with late gestation pregnant females. Pups may be delivered in transit.
Specialized Inventory
| SW-RF | Quantity 1 - 199 |
| Retired Female Breeder | $558.00 |
Specialized Inventory
| SW-FL | Quantity 1 - 199 |
| Female With Litter | $2,455.00 |
SW Male
SW-M
| Age in Weeks | Quantity 1 - 999 |
| 4 | $240.00 |
| 5 | $256.00 |
| 6 | $280.00 |
| 7 | $304.00 |
| 8 | $328.00 |
| 9 | $344.00 |
| 10 | $360.00 |
Specialized Inventory
| SW-RM | Quantity 1 - 199 |
| Retired Male Breeder | $545.00 |
Pricing - EUR
Murine Pathogen Free (MPF) Health Standard
SW Female
SW-F
| Age in Weeks | Quantity 1 - 999 |
| 3 to 4 | €16,00 |
| 5 to 6 | €19,00 |
| 7 to 8 | €20,00 |
| 9 to 10 | €21,00 |
| 11 to 12 | €31,00 |
Specialized Inventory
| SW-RF | Quantity 1 - 199 |
| Retired Female Breeder | €21,00 |
SW Male
SW-M
| Age in Weeks | Quantity 1 - 999 |
| 3 to 4 | €16,00 |
| 5 to 6 | €19,00 |
| 7 to 8 | €20,00 |
| 9 to 10 | €21,00 |
| 11 to 12 | €31,00 |
Specialized Inventory
| SW-RM | Quantity 1 - 199 |
| Retired Male Breeder | €21,00 |
Opportunist Free (OF) Health Standard
SW Female
SW-F
| Age in Weeks | Quantity 1 - 999 |
| 3 to 4 | €35,00 |
| 5 to 6 | €38,00 |
| 7 to 8 | €41,00 |
| 9 to 10 | €44,00 |
SW Male
SW-M
| Age in Weeks | Quantity 1 - 999 |
| 3 to 4 | €35,00 |
| 5 to 6 | €38,00 |
| 7 to 8 | €41,00 |
| 9 to 10 | €44,00 |
Germ Free (GF) Health Standard
SW Female
SW-F
| Age in Weeks | Quantity 1 - 999 |
| 4 | €221,00 |
| 5 | €235,00 |
| 6 | €258,00 |
| 7 | €280,00 |
| 8 | €302,00 |
| 9 | €317,00 |
| 10 | €331,00 |
Specialized Inventory
| SW-RF | Quantity 1 - 199 |
| Retired Female Breeder | €558,00 |
SW Male
SW-M
| Age in Weeks | Quantity 1 - 999 |
| 4 | €221,00 |
| 5 | €235,00 |
| 6 | €258,00 |
| 7 | €280,00 |
| 8 | €302,00 |
| 9 | €317,00 |
| 10 | €331,00 |
Specialized Inventory
| SW-RM | Quantity 1 - 199 |
| Retired Male Breeder | €545,00 |
Pricing - USD Nonprofit
Germ Free (GF) Health Standard
SW Female
SW-F
| Age in Weeks | Quantity 1 - 999 |
| 4 | $200.00 |
| 5 | $216.00 |
| 6 | $232.00 |
| 7 | $248.00 |
| 8 | $264.00 |
| 9 | $288.00 |
| 10 | $312.00 |
SW Male
SW-M
| Age in Weeks | Quantity 1 - 999 |
| 4 | $200.00 |
| 5 | $216.00 |
| 6 | $232.00 |
| 7 | $248.00 |
| 8 | $264.00 |
| 9 | $288.00 |
| 10 | $312.00 |
Pricing - EUR Nonprofit
Germ Free (GF) Health Standard
SW Female
SW-F
| Age in Weeks | Quantity 1 - 999 |
| 4 | €184,00 |
| 5 | €198,00 |
| 6 | €214,00 |
| 7 | €228,00 |
| 8 | €243,00 |
| 9 | €265,00 |
| 10 | €287,00 |
SW Male
SW-M
| Age in Weeks | Quantity 1 - 999 |
| 4 | €184,00 |
| 5 | €198,00 |
| 6 | €214,00 |
| 7 | €228,00 |
| 8 | €243,00 |
| 9 | €265,00 |
| 10 | €287,00 |
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Hear From our Scientists
“Success also is facilitated by the use of foster mice that lactate well and readily accept fostered pups. In our experience, germ-free Swiss Webster mice available from Taconic Biosciences are excellent in these respects, as they routinely wean large litters of vigorous pups and rarely reject fostered pups.”
— Schoeb, T. R.; Eaton, K. A. Gnotobiotics; Academic Press, an imprint of Elsevier: London, 2017.