Model No. | Nomenclature | Genotype |
---|---|---|
14095 | B6;129P2-Ungtm1Tld | Inquire for genotype |
Nomenclature: B6;129P2-Ungtm1Tld
Origin
The Ung knockout mouse was developed in the laboratory of Thomas Lindahl at the London Research Institute. A ung targeting vector, replacing exon 4 with a resistance cassette, was transfected into 129 ES cells. Properly targeted ES cells containing a homologous recombination event were selected, cloned, and injected into C57BL6 blastocysts. Chimeric mice were mated with C57BL6 mice to generate heterozygotes. Heterozygous mice were interbred to generate homozygous Ung-/- mice. Founder lines were backcrossed to C57BL/6. Taconic received embryos from CRT in 2015.
Source: Cancer Research Technology (CRT)
This model is cryopreserved and available for recovery. Models can typically be recovered and delivered to customers within 14-16 weeks after order receipt. Purchase of this model includes perpetual use rights and a deliverable of four mutant animals at the Murine Pathogen Free™ health standard along with a genotyping protocol. For models which include a recombinase gene or multiple alleles, all alleles will be provided, but individual animals may not contain all mutant alleles.
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Initial Publication:
Nilsen et al., 2003. Gene-targeted mice lacking the Ung uracil-DNA glycosylase develop B-cell lymphomas. Oncogene., 22:5381-86.
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Item | Commercial | Nonprofit |
---|---|---|
Cryopreserved Model | $23,100.00 | $14,700.00 |
Cryopreserved models are invoiced upon shipment of recovered animals. Once orders are placed, the full purchase price will be applied if the order is canceled. For orders greater than 4 animals, please contact Taconic for options.
Fees for Taconic Transit Cages™ and freight are in addition to the price above.
Item | Commercial | Nonprofit |
---|---|---|
Cryopreserved Model | €21.000,00 | €13.125,00 |
Cryopreserved models are invoiced upon shipment of recovered animals. Once orders are placed, the full purchase price will be applied if the order is canceled. For orders greater than 4 animals, please contact Taconic for options.
Fees for Taconic Transit Cages™ and freight are in addition to the price above.
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