DBA/1

DBA/1 Inbred Mouse Model
  • Live
  • Mouse
  • Male & Female Available
  • Dilute Brown Non-Agouti
  • Available for direct purchase by CRO
Model No.NomenclatureGenotype
DBA1BO-FDBA/1JBomTac
DBA1BO-MDBA/1JBomTac
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Overview

Nomenclature: DBA/1JBomTac

  • Suitable general-purpose research model for immunology and inflammation research
  • Widely used as a model of autoimmunity, especially collagen-induced arthritis
  • High incidence of mammary tumors

Origin

The DBA inbred model was developed by Dr. C. C. Little of the Jackson Laboratory in 1909. The DBA/1 substrain was generated in 1929. M&B A/S (now Taconic Europe) received stock from Jackson Laboratory in 1993. The mice were derived by embryo transfer in 2005 at Taconic US.

Genetics

Species:Mouse
Strain Type:Inbred
Coat Color:Dilute Brown Non-Agouti
Coat Color Loci: a, Tyrp1b, Myo5ad
Genetic Background:DBA/1
Coat Color Loci: a, Tyrp1b, Myo5ad

Other Genetic Notes:

  • Strain Profile: Anpepb, Car2a, Es1b, Es3c, Esdb, Gpi1a, Got2b, Hbbd, Idh1b, Mod1a, Mup1a, Pgm1b, Trfb
  • Immunology: H2q
  • Other: Cd5a, Cd8aa, Cd8bb, Hc1, Thy-1b

Guides & Publications

Applications & Therapeutic Areas

  • Autoimmune Disease
  • Immunology
  • Inflammation

Transit, Housing & Welfare

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Packing Practices

Taconic standard practice is to recombine animals of different home cages and/or ages from a single model and sex during packing, except in specific cases where Taconic's animal welfare policy prohibits recombination due to aggression or other concerns.  When an order is fulfilled with animals from more than one week of birth, this standard practice results in animals from a range of birth weeks packed together in a single TTC. When an order is fulfilled with animals from genotyped models, this standard practice results in animals from different home cages packed together in a single TTC.

Customers who wish to keep animals from different weeks of birth separated should place orders with the special instruction "Divide and label by age."  Note that this special request can result in increased costs for additional Taconic Transit Cages, dividers and/or freight charges.

Taconic discourages other types of custom packing requests as they can have a negative impact on animal welfare. Learn more.

Surgical Models and Services

mouse

Data

Average litter size: 4-6
Lifespan: Lifespan of males is (430 days) but life span of females is long (750 days).

Collagen Induced Arthritis in DBA1 Mice

For some applications, weight may be critical. For orders where weight is critical, please place orders by weight, not by age. Taconic can accept orders by weight for this model. For orders sourced from US or Denmark a production minimum 3 gram span is accepted. All weights are weights at time of packing. Mice and rats can lose weight in transit. Orders for specific weight spans will be assessed a nominal fee. More detail on weight order policies is available.

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n = 250 per sex at MPF health standard from all global colonies.
High and Low represent mean +/- 2 standard deviations.
Based on sample size the charts above represent ~90% of the population.
All growth curves represent animals housed in our barriers, at our standard density and fed NIH31-M diet. Variations at customer facilities will alter expected growth curves.
Growth charts are provided only as a guide.


Customize this chart by clicking the legend elements.

Licensing

Terms of Sale and Use for DBA/1

These models are sold subject to Taconic's Terms and Conditions for Taconic's Models, Products and Services

Pricing - USD

Murine Pathogen Free (MPF) Health Standard

DBA1BO Female

DBA1BO-F

Age in WeeksQuantity 1 - 999
3 to 4$72.00
5 to 7$81.00
8 to 10$93.00

Specialized Inventory

DBA1BO-FLQuantity 1 - 199
Female With Litter$439.00

Specialized Inventory

DBA1BO-UPQuantity 1 - 199
Untimed Pregnant Female$367.00

*Untimed pregnant requests are filled with late gestation pregnant females. Pups may be delivered in transit.

DBA1BO Male

DBA1BO-M

Age in WeeksQuantity 1 - 999
3 to 4$72.00
5 to 7$81.00
8 to 10$93.00

Pricing - EUR

Murine Pathogen Free (MPF) Health Standard

DBA1BO Female

DBA1BO-F

Age in WeeksQuantity 1 - 999
3 to 4€84,00
5 to 7€93,00
8 to 10€105,00

DBA1BO Male

DBA1BO-M

Age in WeeksQuantity 1 - 999
3 to 4€84,00
5 to 7€93,00
8 to 10€105,00

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  • Evaluate a specific model strain, before making any financial investment
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