| Model No. | Nomenclature | Genotype |
|---|---|---|
| SHR | NTac:SHR |
Spontaneously Hypertensive
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Overview
Nomenclature: NTac:SHR
- Derived from the Okamoto-Aoki Strain
- Males exhibit average systolic blood pressures greater than 200 mmHg by 3-4 months of age
- The SHR is generally used for studies in hypertension and cardiovascular research
- Based on historical usage, the SHR has outbred nomenclature NTac:SHR. However, genetic testing has shown that this colony is homozygous at all alleles tested (inbred). Taconic maintains the SHR through random breeding in a closed colony.
Origin
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