Immunology: Complete Blood Cell Count

Routine evaluation of the cellular components of the immune system is performed by automated determination of the absolute numbers and ratios of various cell types in the peripheral blood i.e. complete blood cell count (CBC).

CBC measures include:

• WBC - White Blood Cell Count
• NEUTRO - Neutrophil
• LYM - Lymphocyte
• MONO - Monocyte
• EOS - Eosinophil
• BASO - Basophil
• RBC - Red Blood Cell Count
• HGB - Hemoglobin
• HCT - Hematocrit
• MCV - Mean Corpuscular Volume
• MCH - Mean Corpuscular Hemoglobin
• MCHC - Mean Corpuscular Hemoglobin Concentration
• RDW - Red Cell Distribution Width
• PLT - Platelet
• MPV - Mean Platelet Volume

Displayed below is a sample graph of how CBC values are presented. In comprehensive phenotypic data packages graphs are interactive. Raw or calculated data and statistics can be seen by clicking on points in the graph.

Figure illustrates CBC values for WBC, NEUTRO, LYM (Row 1); MONO, EOS, BASO (Row 2); RBC, HGB, HCT (Row 3), MCV, MCH, MCHC (Row 4); RDW, PLT, MPV (Row 5) for male and female mutant mice. CBC values for wild type littermates (green circle), homozygous mice (red diamond), and recent historical wild types (purple line) are plotted against long-term historical values (± 2 standard deviations) for wild type animals (green shading). Recent wild type values are calculated from data collected within 60 days of current measures and long-term historical values are derived from data collected on more than 10,000 wild type mice.