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From Concept to Colony: Generating & Managing Genetically Engineered Mouse Models  

Fewer than 8% of drug candidates succeed in clinical trials, and choosing the right preclinical models is critical to improving those odds.

With decades of expertise in creating and managing genetically engineered mouse models (GEMs), Taconic Biosciences provides actionable insights to support researchers in designing and managing GEMs that accurately model human disease and improve drug development success rates.

Whether you're new to GEMs or looking to refine your approach, this resource will provide valuable insights for scientists, program managers and drug discovery researchers as you walk through the critical steps in designing and managing GEMs. Unlock the potential of your preclinical research today.


What You'll Learn:

  • Avoiding the pitfalls of traditional "bottom-up" planning by focusing on desired outcomes to achieve superior phenotypes using our top-down approach to model design. 
  • How to compare model generation technologies like CRISPR/Cas9, embryonic stem cell (ESC) targeting, and random insertion techniques to determine the best fit for your needs. 
  • Key considerations for effective colony management, including animal husbandry, genotyping, and cryopreservation, which can save time and enhance research reproducibility. 
  • How Taconic's unique integrated solutions approach streamlines the transition from concept to colony, reducing risk and accelerating timelines while aligning with the 3Rs principles.

 
Top-Down Model Generation Ensures Desired Outcomes

 
Effective Colony Management Saves Time and Resources

 
Integrated Solutions Streamline the Path from Concept to Colony

Why Taconic?

Taconic Biosciences is a global leader in genetically engineered mouse models and colony management services. We support researchers in advancing their science with innovative, reliable solutions. Learn More about our Fully Integrated Custom Model Generation and Colony Management Solutions.

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