Round Up: Top 5 Insights from the Summer 2018

Here's our recap of the top Insight posts from the summer you might have missed!

1. Translational Microbiome Infographic

Are you beginning your studies in the Microbiome and don't know where to start? Download and print out the Translational Microbiome at a Glance Infographic to give you a quick reference into this valuable area of research — Find out more!

3. Limitations of Feces as a Proxy for Gut Microbiota

The gut microbiota can be influenced by a number of factors including diet, stress, circadian rhythm — which all may be a contributing factor to the lack of reproducibility between institutions. Researchers at the University of Missouri subjected a number of outbred mice to different husbandry conditions including cage type, bedding materials, and chow diet.

View the entire Insight — their study findings may surprise you.

5. Evaluating IO Bispecifics with PBMC-Humanized Mice

In this Insight the advantages and disadvantages of using PBMC-engrafted humanized mice in preclinical evaluations of T cell-engaging, bispecific/multispecific cancer immunotherapies are discussed. Review a representative study using real data from late-preclinical and clinical-stage therapies evaluating PBMC-engrafted mice, ideal for any preclinical researcher working on in vivo bispecific studies.