C3H

C3H Inbred Mouse Model
  • Live
  • Mouse
  • Male & Female Available
  • Black Agouti
  • Available for direct purchase by CRO
Model No.NomenclatureGenotype
C3H-FC3H/HeNTac
C3H-MC3H/HeNTac
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Overview

Nomenclature: C3H/HeNTac

 

  • Used as a model for drug treatments of neurologic disorders
  • Applications in infectious disease studies, toxicology, and oncology
  • Homozygous for retinal degeneration Pde6brd1
  •  
Orders by weight: Taconic cannot routinely accept orders by weight for this model due to colony size. Please inquire for options if weight is critical for your experiment.

Origin

The C3H inbred model was developed by Strong et al. in 1920 by intercrossing a Bagg albino female mouse to a DBA male mouse. Andervont received stock from Strong in 1930. Heston received stock at F35 from Andervont. NIH received stock at F57 from Heston in 1951. Taconic received stock at F147 from NIH in 1987. Taconic received breeding stock at F174 from the NIH Animal Genetic Resource in 1998. The mice were derived by embryo transfer. Taconic's C3H mouse is MTV-. The Taconic foundation colony was at F203 in 2005.

Genetics

Species:Mouse
Strain Type:Inbred
Coat Color:Black Agouti
Coat Color Loci: A/A
Genetic Background:C3H
Coat Color Loci: A/A

Other Genetic Notes:

  • Strain Profile: Alada, Car2b, Ce2b, Es1b, Es3c, Esdb, Gpi1b, Gus-sb, H6pd1b, Hbbd, Idhla, Mod1a, Mup1a, Pep3b, Pgm1b, Trfb
  • Immunology: H2k
  • Other: Cd5a, Cd72b, Cd8aa, Cd8bb, Hc1, H2-T18b, Igh-1b, Ptprcb, Thy1b
  • Retinal Degeneration: Pde6brd1

Guides & Publications

Applications & Therapeutic Areas

  • Immunology
  • Infectious Disease
  • Inflammation
  • Microbiome
  • Neuroscience
  • Oncology & Immuno-Oncology
  • Vaccine Research

Transit, Housing & Welfare

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Packing Practices

Taconic standard practice is to recombine animals of different home cages and/or ages from a single model and sex during packing, except in specific cases where Taconic's animal welfare policy prohibits recombination due to aggression or other concerns.  When an order is fulfilled with animals from more than one week of birth, this standard practice results in animals from a range of birth weeks packed together in a single TTC. When an order is fulfilled with animals from genotyped models, this standard practice results in animals from different home cages packed together in a single TTC.

Customers who wish to keep animals from different weeks of birth separated should place orders with the special instruction "Divide and label by age."  Note that this special request can result in increased costs for additional Taconic Transit Cages, dividers and/or freight charges.

Taconic discourages other types of custom packing requests as they can have a negative impact on animal welfare. Learn more.

Data

Average litter size: 7

Licensing

Terms of Sale and Use for C3H

These models are sold subject to Taconic's Terms and Conditions for Taconic's Models, Products and Services

Pricing - USD

Opportunist Free (OF) Health Standard

C3H Female

C3H-F

Age in WeeksQuantity 1 - 999
3 to 4$65.00
5 to 7$69.00
8 to 10$88.00

Specialized Inventory

C3H-UPQuantity 1 - 199
Untimed Pregnant Female$453.00

*Untimed pregnant requests are filled with late gestation pregnant females. Pups may be delivered in transit.

C3H Male

C3H-M

Age in WeeksQuantity 1 - 999
3 to 4$56.00
5 to 7$64.00
8 to 10$74.00

Pricing - EUR

Opportunist Free (OF) Health Standard

C3H Female

C3H-F

Age in WeeksQuantity 1 - 999
3 to 10€74,00

C3H Male

C3H-M

Age in WeeksQuantity 1 - 999
3 to 10€74,00

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